Phentermine and losartan - Methocarbamol Interactions. There are 337 drugs known to interact with methocarbamol, along with 2 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 27 are major, and 310 are moderate.

 
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The metabolism of Lovastatin can be decreased when combined with Glyburide.The metabolism of Phentermine can be decreased when combined with Losartan.The serum concentration of Topiramate can be decreased when it is combined with Glyburide.The metabolism of Lovastatin can be decreased when combined with Losartan.The risk or severity of adverse effects can …Generic Name: meloxicam. Meloxicam is used to treat arthritis. It reduces pain, swelling, and stiffness of the joints. Meloxicam is known as a nonsteroidal anti-inflammatory drug (NSAID). Warnings ...Sep 23, 2022 · Key takeaways: Gabapentin (Neurontin) can interact with medications and substances that make you sleepy. These include opioids, benzodiazepines, and alcohol. Gabapentin can interact with some over-the-counter (OTC) medications and supplements. These include antihistamines as well as products that contain magnesium or aluminum. Generic Name: semaglutide. Semaglutide is used with a proper diet and exercise program to control high blood sugar in people with type 2 diabetes. Controlling high blood sugar helps prevent kidney ...What is Losartan? Losartan has active ingredients of losartan potassium. It is used in high blood pressure. Currently, eHealthMe is studying from 164,729 Losartan users. What is Rosuvastatin calcium? Rosuvastatin calcium has active ingredients of rosuvastatin calcium. It is used in high blood cholesterol. Oct 28, 2022 · Phentermine is best used as part of a multi-faceted weight loss program which includes dietary changes, exercise routines, the right supplements, and other medications. Phentermine can also be combined with hormonal therapy such as testosterone or T3 therapy to help boost weight loss over a short-term period. Background: To evaluate effectiveness, safety, and costs of Lorcaserin vs. phentermine among obese non-surgical and surgical patients (post bariatric surgery). Methods: This retrospective study retrieved charts of all patients (January 2013-June 2016) who received Lorcaserin or phentermine for 3 months. The study assessed anthropometric, glycemic, and lipid changes, as well as side effects and ...Precautions. It is very important that your doctor check your progress at regular visits to allow for changes in your dose and to help reduce any side effects. Blood tests may be needed to check for any unwanted effects. Do not take escitalopram with a monoamine oxidase (MAO) inhibitor (eg, isocarboxazid [Marplan®], linezolid (Zyvox ...To give you an idea of the possibilities: Adipex-P is a 37.5mg tablet or capsule taken once per day, while Lomaira is an 8mg tablet taken up to three times per day, and Suprenza is an ODT taken once per day. Your individual phentermine dosage will be determined by your doctor according to your specific needs and requirements.. …Antidepressants, such as selective serotonin reuptake inhibitors (SSRIs), including Prozac ( fluoxetine ), Celexa ( citalopram ), Lexapro ( escitalopram ), and Zoloft ( sertraline) can cause ...Phentermine may be partially metabolized in the liver. Following administration of a single 15 mg-92 mg dose of phentermine-topiramate, mean phentermine systemic exposure (AUC) was 37% and 60% higher in patients with mild (Child-Pugh score 5 to 6) and moderate (Child-Pugh score 7 to 9) hepatic impairment, respectively, compared to healthy ...the absorption of a drug into the body; distribution of the drug within the body; alterations made to the drug by the body (metabolism); and. elimination of the drug from the body. Most of the important drug interactions result from a change in the absorption, metabolism, or elimination of a drug. Drug interactions also may occur when two drugs ... 56 year old caucasian female, post-menopausal, healthy diet, inability to exercise more than mildly (so just regular activity, frequent walking, everyday tasks etc no problem, full range of motion for non-exertive stuff), obese but not morbidly, taking losartan potassium daily for mild hypertension (a decrease from quite high blood pressure 2 ...Cholecystitis chronic is reported only by a few people who take Losartan and Phentermine. We study 194 people who have side effects while taking Losartan and Phentermine from the FDA. Among them, 1 has Cholecystitis chronic. Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world.Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Data sources include IBM Watson Micromedex (updated 1 Oct 2023), Cerner …Peptic ulcer disease. If you take these medications at the same time as your thyroid medication, it can interfere with how well it works. If you’re taking treatment for stomach acid, your provider may need to increase the dosage of your Synthroid. 6. You started estrogen hormone replacement therapy or birth control.Side Effects. Dizziness, lightheadedness, swelling ankles /feet, or flushing may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly. To lower your risk of ...How Medications Affect Sperm and Male Fertility. A number of things can affect sperm and fertility, such as being overweight or too thin, smoking cigarettes, excessive drinking, genetic factors ...An elevation in the serum creatinine concentration (SCr) usually reflects a reduction in the glomerular filtration rate and is associated with a concomitant rise in the blood urea nitrogen (BUN). (See "Assessment of kidney function" .) There are, however, a variety of settings in which the SCr can increase acutely independent of a decrease in ...Jan 20, 2023 · The following principles inform the management of chronic medications in the perioperative period: A complete medication history should be obtained, and all clinicians involved in patient management (eg, surgeon, anesthesiologist, medical consultants) should review the medication history. Medication use reported by the patient should be ... Dec 24, 2010 · Answer. A Drug Interactions checker indicates that these two drugs have a MAJOR interaction with each other, which, quite honestly is pretty rare. The problem is that wellbutrin is associated with ... Outlook. Some medications, including vitamin A, antibiotics, and chemotherapy, can cause temporary hair loss. Others, including hormone therapy, may cause hair loss that is permanent. BONNINSTUDIO ...Aug 30, 2022 · Potassium-sparing diuretics can also interact with lisinopril in another way. These are diuretics that cause your body to hold onto potassium. Examples include amiloride (Midamor), eplerenone (Inspra), and spironolactone (Aldactone). Both potassium-sparing diuretics and lisinopril can increase potassium levels in your blood. Methods: A prospective, randomized, 3-period crossover study was conducted in 16 healthy volunteers with phenytoin alone, phenytoin in combination with losartan, and losartan …Drug interactions are reported among 8 people who take Losartan potassium and Beet. Common interactions include vomiting among females, and death among males. The phase IV clinical study analyzes what interactions people who take Losartan potassium and Beet have. It is created by eHealthMe based on reports from the FDA, and is updated regularly.Below, we'll discuss a number of medications that may disqualify you from donating blood. 1. Isotretinoin. If you have severe acne, chances are you've heard of isotretinoin (Absorica, Claravis). Isotretinoin is also used off-label to treat other skin conditions, including psoriasis, rosacea, and hidradenitis suppurativa.Narrow Angles and Angle-Closure Glaucoma What is Angle-Closure Glaucoma? Angle-closure glaucoma, the second most common type, is a largely inherited disorder caused by a too-narrow angle in the passageway where aqueous fluid would normally drain.This type of glaucoma may occur in two ways: The chronic type progresses slowly and, like open-angle glaucoma, can …Sun sensitivity is a common side effect of the oral acne medication isotretinoin (Accutane). Isotretinoin makes the skin more sensitive in general. This makes it more likely that you’ll get a sunburn while taking it. 4. Retin-A (tretinoin) Tretinoin (Retin-A) is another acne medication that’s applied topically.13 Drugs That Can Cause Gingival Hyperplasia | AZ Dentist. Sleep Disorders. Gingival hyperplasia, also known as gingival enlargement, is a swelling of the gum tissue (gingiva). Hyperplasia specifically means an increase in the number of cells in the gum tissue. This increase in gingival cells has many different causes, but one of the most ...Berberine is a chemical found in some plants like European barberry, goldenseal, goldthread, Oregon grape, phellodendron, and tree turmeric. Berberine is a bitter-tasting and yellow-colored ...An elevation in the serum creatinine concentration (SCr) usually reflects a reduction in the glomerular filtration rate and is associated with a concomitant rise in the blood urea nitrogen (BUN). (See "Assessment of kidney function" .) There are, however, a variety of settings in which the SCr can increase acutely independent of a decrease in ...From antihistamines to anti-anxiety, and even acne medications, medications that cause bad breath are more common than you think. 1. Phentermine (Adipex-P) Phentermine acts as an appetite suppressant, by affecting the central nervous system. It is used together with exercise and diet to treat obesity.Common side effects of losartan include dizziness, stuffy nose, back pain, diarrhea, tiredness, low blood sugar, chest pain, and high or low blood pressure. An irregular heartbeat (arrhythmia) has been reported with losartan but is rare. The dizziness associated with losartan usually occurs early in treatment or with an increase in dosage.Products 1 - 800 ... Losartan Pot/HCTZ 50/12.5 mg. 06191904090. CGMP Deviations. If you have ... Phentermine Hydrochloride. 06586205390. 06586219899. CGMP Deviations.Products 1 - 800 ... Losartan Pot/HCTZ 50/12.5 mg. 06191904090. CGMP Deviations. If you have ... Phentermine Hydrochloride. 06586205390. 06586219899. CGMP Deviations.1. How it works Losartan may be used to treat high blood pressure or certain types of kidney disease. Losartan works by blocking the effect of angiotensin II, a hormone that causes blood vessels to narrow (constrict) increasing blood pressure. Blocking angiotensin II widens (dilates) blood vessels which lowers blood pressure.Dallas2021 10 Jan 2021. I definitely experience a *tremendous* increase in sex drive after taking phentermine. But, for me, it also causes a very definite inability to maintain or even have an erection. But it's been very effective helping with my weight loss/exercise goals. The universe does enjoy it's little jokes. +0.Drug interactions are reported among 3,869 peopel who take Hydrochlorothiazide and Atorvastatin calcium. Common interactions include procedural pain among females, and diarrhoea among malesUpper Endoscopy and Colonoscopy. Some medications (prescription and over-the-counter) can reduce your body’s ability to form blood clots and taking these before GI endoscopy procedures may increase your risk of bleeding during and after these tests.If you don can you take phentermine with blood pressure meds t tell me amlodipine combination drugs the secret today, don t touch seizure meds low blood pressure me. what causes your systolic blood pressure to be high Samson pretended to yield to her request viagra and blood pressure medication and said to her in a serious manner If I were to bind me with new unused diastolic medication rope ...Allergy to nonsteroidal anti-inflammatory drugs (NSAIDs) (eg, celecoxib, ibuprofen, naproxen, Advil®, Aleve®, or Motrin®)—Continue to avoid aspirin or NSAIDs while taking this medicine. Asthma attack, acute—Should not be used in patients with this condition. Mental health problems, history of—Use with caution. May make this condition ...Tamoxifen Drug Interactions. Tamoxifen, which is prescribed for the treatment of breast cancer, can interact with some commonly used drugs, including over-the-counter and nutritional supplements. You may be taking tamoxifen for at least five to 10 years, so it's important that you discuss its potential interactions with medications that …Summary. Many drugs and medications can affect thyroid function, but only a small subset (glucocorticoids, dopamine agonists, somatostatin analogs and rexinoids) suppress TSH at the level of the hypothalamus or pituitary. Fortunately, the widely used glucocorticoids and the somatostatin analogs do not induce clinically evident central ...Nov 13, 2009 · Phentermine, a stimulant similar to amphetamines, acts on the central nervous system to suppress appetite. It is one of the few drugs approved by the Food and Drug Administration to treat obesity. Losartan belomgs to a class of medications called angiotensin II receptor antagonists. It works by blocking the action of certain natural substances that tighten the blood vessels, allowing the blood to flow more smoothly and the heart to pump more efficiently.Phentermine, a stimulant similar to amphetamines, acts on the central nervous system to suppress appetite. It is one of the few drugs approved by the Food and Drug Administration to treat obesity.Nov 25, 2018 · There is no reported interaction between Losartan & Phentermine. There should not be any problem. However, Phentermine can increase blood pressure. So you may need an increase in dosage of Losartan. That needs to be considered. I hope this information will be helpful. If you have any query, please feel free to ask. Jan 11, 2021 · Potentially serious drug interactions with CBD included. a common blood thinner, warfarin. a heart rhythm medication, amiodarone. a thyroid medication, levothyroxine. several medications for seizure, including clobazam, lamotrigine, and valproate. The researchers further warned that while the list may be used as a starting point to identify ... 1. How it works Losartan may be used to treat high blood pressure or certain types of kidney disease. Losartan works by blocking the effect of angiotensin II, a hormone that causes blood vessels to narrow (constrict) increasing blood pressure. Blocking angiotensin II widens (dilates) blood vessels which lowers blood pressure.Aug 17, 2022 · They treat many of the same medical conditions and include medications like losartan (Cozaar) and valsartan (Diovan). Like with ACE inhibitors, ARBs may raise your potassium levels by blocking the release of aldosterone. In fact, up to 10% of people will experience hyperkalemia in their first year of taking an ARB or ACE inhibitor. This isn’t an exhaustive list, but here are some common Paxlovid interactions to be aware of. 1. Statins. Statins are common medications that lower high cholesterol. Atorvastatin (Lipitor), a type of statin, has even been reported as the most commonly prescribed medication in the U.S.There are 10 disease interactions with progesterone which include: breast malignancy. liver disease. thromboembolism. depression. fluid retention. glucose intolerance. retinal thrombosis. thyroid function tests.Phentermine (Adipex®, Suprenza®) Phentermine / Topiramate (Qsymia®) Discontinue at least 7 days preop Risk of hypotension that is unresponsive to treatment. Other Medical patches Estrogen patch Nicotine patch Continue Herbal Supplements See list Discontinue at least one week preop Risk of bleeding, blood pressure problems, slow awakening from The prescription reads: Losartan/HCT 100-12.5mg tab lup, 1 tab by mouth in the morning. JACUSTOMER-n7ncb69c- : This medication is photosensitive. He needs to avoid prolonged exposure to sunlight and if he is in the sun he needs to wear sunblock and protective clothing. Some blood pressure medications in the heat and sun reduce ability …From antihistamines to anti-anxiety, and even acne medications, medications that cause bad breath are more common than you think. 1. Phentermine (Adipex-P) Phentermine acts as an appetite suppressant, by affecting the central nervous system. It is used together with exercise and diet to treat obesity.I am a 28 year old male, 6'3 300lbs. I am currently taking Losartan 25 MG 1 daily for hypertension. My PCP just prescribed me with phentermine 37.5 MG for weight loss which also raises BP. Is it safe for me to take both medications together ? Should I increase the mg for my losartan?Levetiracetam Interactions. There are 233 drugs known to interact with levetiracetam, along with 4 disease interactions, and 1 alcohol/food interaction.Of the total drug interactions, 5 are major, 225 are moderate, and 3 are minor.2 thg 6, 2020 ... Phentermine (Duromine). Orlistat (Xenical). Digestive supplements ... losartan). Withhold. Continuing may increase peri-op hypotension. Withhold ...Narrow Angles and Angle-Closure Glaucoma What is Angle-Closure Glaucoma? Angle-closure glaucoma, the second most common type, is a largely inherited disorder caused by a too-narrow angle in the passageway where aqueous fluid would normally drain.This type of glaucoma may occur in two ways: The chronic type progresses slowly and, like open-angle glaucoma, can …Stacy asked. I take levothyroxine 25mcg, doxycycline hyclate 50 mg (for dry eyes/meibomian gland dysfunction), and fluoxetine (Prozac) 20 mg everydayI know the levothyroxine needs to be taken on an empty stomach.Cozaar, Hyzaar (Losartan); Diovan, Exforge (Valsartan); Edarbi (Azilsartan) ... Weight Loss / Management (Diet) – Dexfenfluramine (Redux), Fenfluramine (Pondimin), ...Jan 27, 2023 · Promethazine, a prescription-only nausea medication, can cause bodywide rashes that appear after sun exposure. In some cases, these rashes continued to come and go for weeks or months after stopping the medication. 9. Methotrexate. Methotrexate can be prescribed for different autoimmune disorders and cancers. There are 17 disease interactions with phentermine. Cardiovascular Glaucoma Agitation Cardiac disease Glaucoma Hypertension Liver disease Psychiatric disorders Pulmonary …May 26, 2010 · Dallas2021 10 Jan 2021. I definitely experience a *tremendous* increase in sex drive after taking phentermine. But, for me, it also causes a very definite inability to maintain or even have an erection. But it's been very effective helping with my weight loss/exercise goals. The universe does enjoy it's little jokes. +0. Serious side effects of losartan oral tablets that have been reported include: high level of potassium in your blood. kidney problems, such as acute (sudden) kidney failure. allergic reaction ...Using phentermine with alcohol can increase the risk of cardiovascular side effects such as increased heart rate, chest pain, or blood pressure changes. In addition, you may also be more likely to experience nervous system side effects such as dizziness, drowsiness, depression, and difficulty concentrating. You should avoid or limit the use of ...Doxycycline Interactions. There are 202 drugs known to interact with doxycycline, along with 3 disease interactions, and 2 alcohol/food interactions.Of the total drug interactions, 21 are major, 176 are moderate, and 5 are minor. Bactrim disease interactions. There are 12 disease interactions with Bactrim (sulfamethoxazole / trimethoprim) which include: colitis. hematologic toxicity. hypersensitivity reactions. liver disease. porphyria. renal dysfunction. folate deficiency.Apr 22, 2022 · Aspirin and nonsteroidal anti-inflammatory drugs (NSAIDs) like naproxen (Aleve) and ibuprofen (Motrin, Advil) can cause ringing in the ears and hearing loss when used at high doses and/or for long periods of time. However, this effect appears to be reversible when you stop using these medications. Consult with your pharmacist before taking any new medication or supplement alongside phentermine. 5. Blood Pressure Medications. Phentermine may cause a significant increase in blood pressure. Later, weight loss may decrease need for blood pressure medications. Tell your doctor if you any take any medications for blood …Drug-condition interaction. This is when you have a health problem that makes it risky for you to take certain meds. For example, if you have a condition like high blood pressure, …Below, we'll discuss a number of medications that may disqualify you from donating blood. 1. Isotretinoin. If you have severe acne, chances are you've heard of isotretinoin (Absorica, Claravis). Isotretinoin is also used off-label to treat other skin conditions, including psoriasis, rosacea, and hidradenitis suppurativa.phentermine hcl oral. E pregabalin oral. 1. QL. QSYMIA. E. RADICAVA. 3. PA; SP. RILUTEK ... losartan potassium-hctz............53. LOSEASONIQUE...................Dallas2021 10 Jan 2021. I definitely experience a *tremendous* increase in sex drive after taking phentermine. But, for me, it also causes a very definite inability to maintain or even have an erection. But it's been very effective helping with my weight loss/exercise goals. The universe does enjoy it's little jokes. +0.Promethazine, a prescription-only nausea medication, can cause bodywide rashes that appear after sun exposure. In some cases, these rashes continued to come and go for weeks or months after stopping the medication. 9. Methotrexate. Methotrexate can be prescribed for different autoimmune disorders and cancers.Drug-induced liver injury (DILI) is a challenging diagnosis since a wide variety of medicines can cause adverse reactions. Losartan is an angiotensin II receptor antagonist (ARA-II) approved for the treatment of arterial hypertension. The most common adverse effects are fatigue, anaemia, weakness and cough. An increase in transaminases has been ...Dec 19, 2017 · Drugs that are likely to interfere with tamoxifen. Alternative drugs that should be safe to take with tamoxifen. Antidepressants (SSRI/SNRIs) Paxil, Prozac, Wellbutrin, and Cymbalta. Effexor, Pristiq, Edronax, Lexapro, and Remeron. Antipsychotics. Mellaril, Trilafon, and Orap. Using phentermine with alcohol can increase the risk of cardiovascular side effects such as increased heart rate, chest pain, or blood pressure changes. In addition, you may also be more likely to experience nervous system side effects such as dizziness, drowsiness, depression, and difficulty concentrating. You should avoid or limit the use of ... What is Losartan? Losartan has active ingredients of losartan potassium. It is used in high blood pressure. Currently, eHealthMe is studying from 164,729 Losartan users. What is Rosuvastatin calcium? Rosuvastatin calcium has active ingredients of rosuvastatin calcium. It is used in high blood cholesterol.Bupropion is one medication that lowers the seizure threshold. The risk is greater with the IR form and with higher doses. Typical doses of bupropion (450 mg per day or less) are not as likely to cause seizures as higher doses. And starting at a lower dose and increasing it slowly helps lower the risk.Medications that raise potassium levels. Potassium is an electrolyte that’s …Losartan and valsartan are angiotensin receptor blockers that work by blocking angiotensin II that causes blood vessels to constrict.This causes blood vessels to dilate which helps reduce blood pressure and the workload on the heart.; Both losartan and valsartan are used to treat high blood pressure (hypertension).; Losartan is also used to reduce the risk of stroke in patients with high blood ...11 /11. Several of these medications for mental disorders can lead to false positive tests. Quetiapine, which treats schizophrenia and bipolar disorder, can wrongly show that you have methadone in ...

Doxycycline Interactions. There are 202 drugs known to interact with doxycycline, along with 3 disease interactions, and 2 alcohol/food interactions.Of the total drug interactions, 21 are major, 176 are moderate, and 5 are minor.. Www jcrewfactory

phentermine and losartan

Drug interactions are reported among 3,869 peopel who take Hydrochlorothiazide and Atorvastatin calcium. Common interactions include procedural pain among females, and diarrhoea among malesphentermine. 1 interaction. losartan (generic). +. phentermine. Monitor/Modify Tx. losartan + phentermine. monitor BP: combo may decr. antihypertensive agent ...Retinopathy is a well-characterized side effect of treatment and includes cotton-wool spots, intraretinal and pre-retinal hemorrhage, and macular edema (See Figure 3).A wide incidence range of 18 percent to 86 percent has been reported for interferon retinopathy. 24 Signs develop within two weeks to three months of treatment onset; patients may complain of blurred vision or be entirely ...Changing how the world understands and treats cancer. Our scientists pursue every aspect of cancer research—from exploring the biology of genes and cells, to developing immune-based treatments, uncovering the causes of metastasis, and more. Weight loss/CNS Stimulants Phentermine 11 APPENDICES Appendix A: Immunosuppressant and Antirheumatic Agents 12 Appendix B: ... ARB: losartan, valsartan, candesartan, irbesartan If dosed in the evening hold evening dose night prior to surgery. Do not take the night before or day of surgery.MiraLAX Interactions. There are 215 drugs known to interact with MiraLAX (polyethylene glycol 3350), along with 3 disease interactions. Of the total drug interactions, 214 are moderate, and 1 is minor.Consult with your pharmacist before taking any new medication or supplement alongside phentermine. 5. Blood Pressure Medications. Phentermine may cause a significant increase in blood pressure. Later, weight loss may decrease need for blood pressure medications. Tell your doctor if you any take any medications for blood …Some brands of phentermine should be taken between half an hour and an hour before breakfast, while others are taken within two hours of eating your first meal. These instructions will vary with different phentermine pills. If you’re taking a smaller dose (or splitting tablets), you will take your phentermine up to three times per day.After looking closely at the drug-drug interactions listed for the new oral COVID-19 drug, Paxlovid, I realized that a large percentage of my patients are taking medications on the list.. Patients with hypertension, coronary artery disease, atrial fibrillation, and hyperlipidemia should pay close attention to what follows if they are considering …There are 174 drugs known to interact with phentermine, along with 17 disease interactions, and 3 alcohol/food interactions. Of the total drug interactions, 43 ...Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Data sources include IBM Watson Micromedex (updated 1 Oct 2023), Cerner …Acne. SkyMD allows patients to go to an online doctor at their convenience with no doctor's appointment. Patients can consult a dermatologist anytime, anywhere in minutes. SkyMD's board certified dermatologists are treating patients every day across the country, 24 x 7, with many different skin diseases.phentermine topiramate. Applies to: Qsymia (phentermine / topiramate) and Qsymia (phentermine / topiramate) Topiramate may increase the blood levels and effects of …Tamsulosin Interactions. There are 289 drugs known to interact with tamsulosin, along with 4 disease interactions, and 2 alcohol/food interactions.Of the total drug interactions, 32 are major, 253 are moderate, and 4 are minor. May 12, 2023 · Some brands of phentermine should be taken between half an hour and an hour before breakfast, while others are taken within two hours of eating your first meal. These instructions will vary with different phentermine pills. If you’re taking a smaller dose (or splitting tablets), you will take your phentermine up to three times per day. Bactrim disease interactions. There are 12 disease interactions with Bactrim (sulfamethoxazole / trimethoprim) which include: colitis. hematologic toxicity. hypersensitivity reactions. liver disease. porphyria. renal dysfunction. folate deficiency..

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